So, I started a new cycle coming out of a post-show cruise phase of TRT level dose of Test E for 6 weeks. I started with EOD injections of the following, with an intent to ramp up the dosing after 2 weeks and then again after 4 weeks. After these first two weeks, I am feeling great, bloodwork is great, and my strength and gains in the gym is unmatched. For that reason, I think I will stay put, employing the "least effective dose" discipline.
I should note that my last cycle turned out to eventually become a disaster with spiked E2 levels and crashed sex hormone due to too much test w/o EQ or an AI. I was counting on Mast helping with E2, but that did not happen. For those who know, you are fucked once your E2 spikes to a crazy level. You can barely find energy to move much less workout.
Here is my current dosing:
Test E 450 mg/wk (150 mg EOD)
NPP: 100 mg EOD
Deca: 150 mg /wk (50 mg EOD)
EQ: 150 mg/wk (50 mg EOD)
I am using the EQ really just to control my E2. I was ramping up Deca and doing 150 mg/wk for firt 4 weeks with NPP so the Deca, a long acting ester, could set in. I am going to ditch the NPP in week 5 and put the Deca at 300 mg/wk. (I don't suffer Deca sides, so I am blessed to easily use this compound).
I am going to keep my Test E at 450 mg/week and EQ at 150 mg/wk, just pushing the Deca a bit higher to 300 mg/wk in week 5.
Moral of my story is that for me, this seems to be a "sweet spot." Everyone is different, but I pushed 1g of Test E w/ Deca at 600 mg/wk and Mast at 500 mg/wk, and this spiked my E2 ridiculously. At my current levels, I am training hard, growing in a lean way, and my bloodwork is great.
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Hey buddy, I'm glad you found a dose that works for you instead of just trying to increase it. If your strength is going up, you're making progress, and your bloodwork looks good, I would keep things as they are. Your last cycle shows that using more doesn't always lead to better results. I hope things stay steady as you fully switch to Deca.
Spot on, @Tommy. The "Least Effective Dose" (LED) is the ultimate sign of a mature researcher.
What you experienced on your last cycle the 1g Test disaster is a textbook case of reaching the "Point of Diminishing Returns." When you push raw milligrams that high, especially with UGL gear that often carries residual solvents and unverified purity, you aren't just fighting Estrogen; you're fighting systemic inflammation. That "crushed" feeling you had wasn't just E2 it was your immune system and CNS being redlined by the impurities in the oil.
The reason you’re feeling "unmatched" strength now on 450mg is simple: your androgen receptors aren't being drowned in "noise."
When the compound is high-purity (99%+), the binding affinity is much cleaner. Your body spends zero energy fighting the vehicle (carrier oil/solvents) and 100% of the energy on protein synthesis and neural drive.
A few technical notes on your current stack:
1. Smart use of EQ as an aromatase inhibitor substitute. It’s much easier on the lipids than letrozole or high-dose adex.
2. Replacing NPP with Deca in week 5 is a solid transition for stable serum levels, but keep an eye on that 300mg Deca dose if you notice any sudden change in "mood" or prolactin-related blurriness, 200mg is often plenty when the gear is pharma-grade.
Less is more when the quality is higher. Keep riding that sweet spot, brother.
Thanks for the feedback. Appreciate this community.