For those who have followed the research closely, do you think the glucagon component is what makes it particularly interesting compared with the older GLP-1 based compounds, or is the difference being overstated?
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The glucagon aspect stands out as one of the more interesting differences, but some people make it seem like it’s the only factor behind the results. Triple agonism actually creates a different overall effect, not just a stronger version of GLP-1.
Based on what I’ve read, glucagon activity might help with energy use and fat metabolism, while GLP-1 and GIP mostly affect appetite and metabolism. It’s still unclear if this will offer a big real-world benefit over the newer GLP-1/GIP drugs, so I’d like to see more data. Still, the early results are interesting.
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