Ostarine Complete Profile, Dosage, and Other Relevant Information

Table of content

  1. What is Ostarine?
  2. How Does Ostarine Work?
  3. Uses of Ostarine (MK-2866):
  4. Effectiveness
  5. Safe usage
  6. Clinically proven benefits of Ostarine
  7. Ostarine Side Effects 
  8. Dosing
  9. Is Ostarine Legal? 

What is Ostarine?

Ostarine, or MK-2866, is one of the best research compounds designed to treat autoimmune disease and cancer patients suffering from muscular dystrophy, but bodybuilders also now use it. Ostarine is a selective androgen receptor modulator (SARM), and it binds to androgen receptors, proteins found throughout the body. Ostarine instructs muscles to develop when it connects to these receptors. Ostarine is used for various illnesses, including breast cancer, involuntary weight loss due to sickness, and athletic performance. However, there isn't any solid scientific proof to back up these claims. It is a member of the group of medications known as selective androgen receptor modulators, which are intended to replicate the benefits of anabolic steroids while having fewer negative effects. Ostarine can assist you in gaining muscle growth without creating any negative side effects by directly activating androgen receptors in the skeletal muscle tissue throughout the human body. Ostarine is the most thoroughly studied, comprehended, and well-tolerated SARM. 


Molar Mass


Chemical Formula


Routes of administration

By mouth

Elimination half-life

24 hours


3-(4-cyano phenoxy)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methyl propanamide

How Does Ostarine Work?

Ostarine functions by binding to androgen receptors, which are proteins in your body. Your muscles are instructed to develop and get stronger by these receptors. Athletes and bodybuilders use ostarine because it can change your body's composition, meaning you'll have more muscle and less fat. Ostarine can also boost your energy and power and speed up your recovery after exercise.

It works shortly after consumption, quickly targeting and binding to androgen receptors in key skeletal muscle tissues throughout the body.  Ostarine MK 2866 is a selective androgen receptor modulator or SARM that works by targeting androgen receptors on a selective basis. Unlike anabolic steroids or testosterone, it mainly focuses on the muscle and bone tissue. 
This selectivity enables Ostarine to avoid a wide range of intense side effects and has allowed researchers to study this SARM in female and elderly test subjects. However, long-term and randomized human trials are needed to verify its safety.

Uses of Ostarine (MK-2866)

Lean body mass may be dramatically increased by using ostarine. As a result, it has become a go-to for those with muscle-wasting syndrome brought on by cancer and other autoimmune diseases.

  • By utilizing Ostarine, patients with age-related progressive loss of muscle mass and strength-related symptoms might benefit greatly.
  • It has also shown promise in treating hereditary muscular dystrophy, muscle loss or weakening disease.
  • Although there is less proof, it has also demonstrated improvements in breast cancer, incontinence, or loss of bladder control symptoms. Additionally, it is employed to treat cancer patients' muscular wasting. While on bulking and reducing cycles, many bodybuilders use it to boost strength, increase muscle growth, and speed up fat loss.


Ostarine has reportedly been shown to enhance physical performance, prevent muscle loss, and promote muscle growth. Users reported improved strength and gym performance during an 8–12 week Ostarine cycle.

Safe usage

Ostarine can be taken practically every day at any moment because it should be taken every 24 hours. You should, however, refrain from ingesting Ostarine during or shortly before your workouts. Take it in the morning or just after your workout for optimal results.

Clinically proven benefits of Ostarine

Here are some of the clinically proven benefits of Ostarine: 

  • Improve Athletic Performance
  • Lose Abdominal Fat
  • Rapid Strength & Muscle Gains
  • Enhanced Physical Function
  • Grow-Lean Muscles
  • No Muscle Loss While Cutting
  • Huge lean muscle mass
  • Increased muscle endurance
  • Increase energy
  • Increased bone density
  • Faster muscle recovery


1- Increased Muscle Mass Growth

Ostarine MK2866 helps build your muscle mass, but it also works by binding to androgen receptors in your body, which signals the cells to start making great muscle fibers. It helps in increasing muscle mass and endurance. One of the best parts about consuming this medication over other muscle-building supplements is that it has since targeted the muscle tissue precisely without affecting other tissues. This makes it a completely safe and more effective alternative to other steroids. But you must know that even if it is beneficial, the results are not entirely out, and clinical trials are still not on the way.

2- Improve Bone Density 

Ostarine MK2866 has shown some improvement in bone density which is especially beneficial for older adults at risk of osteoporosis. It generally improves osteoblasts production, the cells responsible for building bone tissue. It leads to better bones and minimum risk of factors besides other bone-related injuries. Additionally, Ostarine MK2866 can help protect against muscle mass loss commonly linked to ageing.

3- Fat loss

Ostarine MK2866 can help reduce body fat levels by enhancing the body's metabolic rate. It means that the body burns more calories even while it is at risk, which can lead to a decrease in overall body fat levels. Ostarine MK2866 has also been shown to target all fat tissues, especially without affecting muscle tissue. This makes it perfect for bodybuilders and athletes looking forward to getting rid of extra fat without losing muscle mass.

Ostarine Side Effects

There are some minor MK 2866 side effects some might experience: 

  • Liver Damage (on high dosage)
  • Increased Cholesterol
  • Increase Blood Pressure
  • Acne

Side effects

1- Testosterone suppression

One of the significant side effects of Ostarine MK2866 is that the supplement suppresses natural testosterone production. This happens as the accessories end up working by binding to androgen receptors in your body which can signal the body to minimize its production of testosterone is one of the most important hormones for muscle growth, bone density, and of course, overall health, so any reduction in this hormone can lead to several adverse side effects like tiredness minimum sex drive decreased muscle mass and other ailments.

2- Acne and skin issues

One of the side effects of Ostarine MK2866 is skin and acne issues. It happens mainly because Ostarine MK2866 answers the body's production of sebum, one of the oily substances that can clog your pores and lead to acne breakout. Besides acne, some people might also experience skin issues like dry skin irritation and skin rashes.

3- Headaches and nausea

Some people can also experience headaches and nausea after consuming Ostarine MK2866. This happens because Ostarine MK2866 can affect the central nervous system and cause brain chemistry changes. While these effects are usually mild and go away all by themselves, they can be a sign that the body is not tolerating the supplement well and should be adjusted or discontinued.

4- Cardiovascular ailments

Ostarine MK 2866 has been shown to enhance lousy cholesterol levels in people who consume this supplement. This side effect can enhance the risks of cardiovascular ailments like a heart attack or even stroke. Besides this, the supplement can improve blood pressure in some people, and they should be cautious while consuming it. People must consult with the healthcare professional before making this appointment.

5- Liver toxicity

Ostarine MK 82866 is not known to be utterly toxic to your liver, but some studies show that it can lead to liver damage in people, which is more likely to happen with people overdosing on the supplement for a long time. If you have a history of liver ailment, you should be very careful while taking Ostarine MK H2866 and always consult your health expert before using the same.

6- Gynecomastia

In men, the enlargement of breast tissue is called Gynecomastia, and it can be a possible side effect of Ostarine MK 2866. It happens because the supplement can enhance the production of estrogen, and people this side effect is very likely to happen in people who take a huge dose of Ostarine MK2866 for a long time.

7- Hair loss

Hair loss is another side effect of Ostarine MK2866. This can cause changes in the body's hormonal balance, leading to hair loss in some people. Furthermore, the side effect is most likely in people three disposed to hair loss or who take high doses of Ostarine MK2866 for a long time.

8- Liver problems

Some people may get liver issues from ostarine. Ostarine is not recommended for anyone with a history of liver issues.

9- Chest pain

It could be risky to consume orally. Along with other harmful side effects like a heart attack, it may harm the liver.


Most bodybuilders advise that taking 10 to 50 mg of ostarine daily is safe. 

Of course, eating high dosages of ostarine will boost muscle dryness, muscular growth, fat loss, and overall results, but it also increases the likelihood of negative effects. 

  • 10 milligrams per day for beginners
  • 25 mg/day is a medium dosage.
  • 50 mg/day, for experts 

Adults have taken ostarine most often in oral dosages of 3 mg daily for 12–16 weeks. The ideal dosage for a certain ailment should be discussed with a healthcare professional.

Is Ostarine Legal?

Ostarine and other SARMS are banned by the World Anti-Doping Agency (WADA) and the National Collegiate Athletic Association (NCAA).

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