KPV is considered to be the next big thing in anti-inflammatory treatments.
The coolest thing about KPV? It shows promising results in treating conditions like inflammatory bowel disease and asthma and even inhibiting tumor growth in colon cancer. Plus, it does this without resisting the immune system's natural function, a game-changer in the world of anti-inflammatory medications.
Administration: KPV can be administered orally or via injection without severe side effects.
Working Mechanism: It works differently by directly interacting with inflammatory pathways inside cells.
Hey Raise, I read what you wrote in such a precise way, and it includes all the important info we should know, obviously. I want to share a few studies that have been done on it and yield a few results too.
In studies, KPV peptide was reported to exert a more potent anti-inflammatory effect than α-MSH itself.
A study found that when taken orally, KPV can lessen the inflammatory reactions of immune cells and colonic epithelial cells, as well as lower the incidence of colitis in vivo. KPV significantly reduced NO release and TNF-α mRNA expression in glial cells stimulated with beta-amyloid or interferon-gamma.
It is important to note that the anti-inflammatory outcomes of KPV appear to be mediated through somewhat different mechanisms than those of α -MSH. Whereas α -MSH binds to specific melanocortin receptors, KPV does not. KPV works to reduce inflammation inside cells by deactivating inflammatory pathways. Evidence of this comes from mouse studies in which blocking. MC3/4 receptors, which mediate the anti-inflammatory effects of the α -MSH have no impact on the anti-inflammatory properties of KPV. Specifically, blocking these receptors does not block the leukocyte migration effects induced by KPV.
The ability of KPV to be administered by various methods is also appealing over alpha-MSH, which is only an injection. KPV can be used orally by injection without side effects.
I hope these case studies help everyone get a better idea of this peptide
https://steroidwiki.com/forum/post/6333/