5 Alpha Hydroxy Laxogenin Usage, Dosage, Benefits and Side-effects

A Complete Guide to 5 Alpha Hydroxy Laxogenin 

Table of Content

  1. Introduction
  2. Other names for 5 alpha hydroxy laxogenin
  3. Overview
  4. Mechanism of Action
  5. Who can use this plant steroid?
  6. Effective Clinical Dose
  7. The Cycle of 5-alpha-hydroxy laxogenin
  8. 5-Alpha Hydroxy Laxogenin Stacking
  9. Perks of 5 Alpha Hydroxy Laxogenin
  10. Few Side Effects of 5 Alpha Hydroxy Laxogenin

Disclaimer: SteroidWiki doesn’t promote unlawful usage of any chemical compound. The knowledge presented in this article and on the website is purely for educational purposes. If you intend to use the information provided in this article for any purpose, please make sure to check & comply with the laws of your country or area.

To find out the reality behind the claims, we will examine this chemical in greater detail in our guide. If you want to know whether you should use it or not, please keep reading.


The majority of athletes and bodybuilders are often exploring for techniques to increase lean muscle mass without increasing fat in their bodies. One of the easiest shortcuts to do so is the use of anabolic steroids; perhaps the long-term use of steroids can lead to several side effects. Also, once you stop using steroids, the body structure doesn’t stay the same, and it is unable to maintain it without steroids.  

Many other supplements help fitness enthusiasts maintain their figure without severe side effects. Recent research has represented that a plant derivative has all the same properties as anabolic steroids, but the only difference between these two is the severity of the side effects. This plant derivative is known as 5 Alpha Hydroxy Laxogenin or 5 alpha hydroxy laxogenin. This compound is sold in the market in powdered form as a bodybuilding supplement because of its several advantages.

Other names for 5alpha hydroxy laxogenin:

  • 5-alpha-hydroxy-laxogenin
  • 5a-hydroxy-laxogenin
  • 5-laxogenin
  • 25-R-spirostan-5a-diol-6-one-3-one
  • (25R)-3beta,5alpha-dihydroxyspirostan-6-one
  • 25R spirostan-5a-diol-6-one-3-one decanoate
  • 25R spirostan-5a-diol-6-one-3-one undecanoate

Structural Formula


Laxogenin was first revealed in the 1960s as a part of a plant-based steroid group known as brassinosteroids.  This chemical which is found in plants, helps in the growth of plants. Laxogenin, also known as 5 alpha hydroxy laxogenin, is sold for medical purposes in the market. This compound is getting popular day by day amongst the bodybuilding community for its muscle-enhancing properties. Brassinosteroids are functionally and structurally the same as animal and human steroid hormones. Because of this advantage, it is substituting anabolic steroids.

5 alpha hydroxy laxogenin is not a steroid or a prohormone; it is SARM-Selective Androgen Receptor Modulators. It functions differently in the body without affecting hormones, either.

The two primary functions displayed by Brassinosteroids in Laxogenin are:

  • Increased Protein Synthesis
  • Decreased Stress Hormone (Cortisol)

These two features give this remarkable substance a distinct advantage over every other muscle-building supplement on the market.

Supplement facts

Mechanism of Action 

Plants steroids have different methods of functioning in the human body. They operate by stimulating protein synthesis and avoiding muscle protein breakage. This substance binds to the receptor and triggers a signalling chain, which leads to a significant improvement in the body's capacity to develop muscle, as opposed to simply passing through the membrane and causing a change on its own. 5 Alpha Hydroxy Laxogenin activates the particular protein which is protein kinase B or AKT 1. These two substances are responsible for increasing the production of lean muscle mass in the body. Extensive exercise breaks down muscle proteins; however, it is speculated that the benefits of 5-alpha-hydroxy laxogenin also include preventing this. Another significant action of 5 Alpha Hydroxy Laxogenin that attracts bodybuilders and athletes is blocking the breakdown of an important enzyme called cAMP. The increase of this enzyme in the body can lead to the melting off of extra stubborn fat. On the other hand, this enzyme increase results in improved fight or flight response.

 Who can use this plant steroid?

The use of 5 Alpha Hydroxy Laxogenin powder should be considered by bodybuilders, athletes, and anyone who wants to increase muscle mass and tone while lowering body fat levels. As it does not influence Hypothalamic Pituitary Testicular Axis HPTA, it can be consumed by anyone, including females.

Effective Clinical Dose

The right dosage depends on a couple of factors, including the consumer’s age, health, medical history and other conditions. However, according to the research 5 alpha hydroxy laxogenin dosage can start from 100 mg to 200 mg per day. Most people start it from 200 mg per day as they think it will give them optimum outcomes and effects.

The other way to consume this compound is to take a 25mg capsule form thrice or 6 times a day. That makes 75mg to 150mg per day consumed at a specific time. Consuming supplemental powder with meals is advisable because it easily absorbs in the stomach. It can be taken in the morning with a meal or pre-workout, but the timing is not essential for laxogenin. Do not skip the dose, and be sure you take it consistently.

 The Cycle of 5-alpha-hydroxy Laxogenin

Based on its user’s experiences and observations, the cycle can be done for 6 to 12 weeks. 5 Alpha Hydroxy Laxogenin can be consumed for up to 3 to 4 months because it is when the results will be noticeable. It is essential to wait two to four weeks, at the very least after your cycle is over, before beginning a new one. This plant steroid is taken continuously for an extended period until a user notice desirable results. 5-alpha-hydroxy laxogenin is a natural substance which means it can be used for a longer length of time because it has no impact on the body's hormone levels. It doesn’t require any Post Cycle Supplement as well.

5-Alpha Hydroxy Laxogenin Stacking

This compound can be stacked with other steroids and SARMS to enhance muscle growth, increase energy and improve endurance. It is optional to stake Laxogenin with other potent supplements. There have been few studies that represent that users stacked it with Sapogenix or Arachidone. The ideal supplementation for a bulking cycle is laxogenin combined with RAD-140 Sarm.

Perks of 5 Alpha Hydroxy Laxogenin

Now let's talk about the advantages, which are the reason you initially explored this plant steroid. After reading the above content, you may have finally realized why this compound is increasingly popular among fitness enthusiasts. Apart from performance enhancement, based on anecdotal experiences, laxogenin will help one with the following:

  • Enhanced Muscle growth
  • Improved protein synthesis
  • Stable blood sugar levels
  • Better and quick muscle recovery

Many consumers of this supplement adore this because it does not interfere with the endocrine system, so, no suppressed hormones. It also helps to exhibit anti-inflammatory effects, which is good for people facing muscle injuries. This lucrative aspect allows athletes and bodybuilders to exercise with full intensity without muscle pain and uneasiness. Therefore, Post Cycle Therapy is not required after executing the 5 Alpha Hydroxy Laxogenin cycle.

Besides these benefits of this plant steroid, it also provides cortisol support. This helps in fast recovery and prevents muscle breakdown. After its usage, people claim to observe an increase in strength within 3 to 5 days. Muscle mass increased in 3 to 4 weeks. It doesn’t ruin natural hormone balance; hence testosterone level is not affected in the body. Laxogenin is thought to promote protein synthesis and boost nitrogen retention, both of which can aid in developing and maintaining muscle tissue. Laxogenin helps to stabilize high blood sugar levels as well.

Few Side Effects of 5 Alpha Hydroxy Laxogenin

Now that we've demonstrated the effectiveness of using 5 alpha hydroxy laxogenin, you probably want to know if it has any negative side effects. The most important thing about this substance is its no severe side effects. But if people misuse it or take high dosages, they might suffer from headaches, according to anecdotal experiences. If you are willing to use it for muscle development, discuss it with your doctor and let them know your medical conditions. If you want to advance your appearance and performance properly, try Laxogenin for yourself! It's necessary to go over the use of any new supplement with your medical professional.

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Webmd. (2023). Laxogenin - Uses, Side Effects, and More. Webmd [online]. Available from: https://www.webmd.com/vitamins/ai/ingredientmono-1567/laxogenin [accessed 19 July 2023].