Steroid Profile: Primobolan (Methenolone)
Table of Contents
OVERVIEW AND HISTORY OF PRIMOBOLAN / METHENOLONE
Primobolan is the trade name for the anabolic steroid Methenolone. It is obtainable to administer through the oral route or parenteral route.
Injectable Primobolan is known as Primobolan Depot/Methenolone Enanthate, and the oral administered drug is known as Methenolone Acetate. It is a very well-known and popular anabolic steroid due to its very mild nature as both an anabolic and an androgenic compound.
Primobolan is carefully considered one of the most capable anabolic steroids and it typically carries an excellent safety standing. This steroid can be used successfully to treat underweight children and premature babies as well without harm. It's also prescribed for osteoporosis and sarcopenia.
Until now, the primary purpose of Primobolan is to treat muscle-debilitating conditions and prolonged exposure to corticoid hormones. It has also proven to be extremely effective in combating malnutrition.
Primobolan properties and specific details were first released and published in 1960. Squibb released the injectable format of Primobolan (Methenolone Enanthate) first in 1962 followed by the official release of the oral variant of Primo (Methenolone Acetate) into the American market in the same year.
It was at that considerable time marketed under the brand name Nibal Depot (for the injectable) and Nibal for the oral variant dosed at 20mg per tablet.
Remarkably afterward, the rights to manufacture the compound were sold in West Germany to Schering. Following this sale of rights, Nibal was removed from the US market, and instead, Schering marketed the compound under the new trade name Primobolan (for both variants).
It subsequently became the quintessential anabolic steroid manufactured by Schering, who then marketed the compound as an internationally exclusive drug, and would never return to the American Market.
An intriguing point to note is that even though Primobolan was never marketed in the United States after Schering had bought the rights to it, it is still listed as an FDA- approved drug. So, American doctors can import the drug for treatments on special orders.
Like many other anabolic steroids at the time, in the early 1990s, it was ultimately removed from all markets and Schering ceased production. Schering is today only sold in a limited select number of countries across the world, such as Spain Turkey, Japan, Paraguay, and Ecuador.
Pharmaceutical grade oral Primo can be located in Japan and South Africa. In general, pharmaceutical-grade oral Primobolan products are even rarer than the injectable, and only small amounts of 5mg and 25mg tablets from Schering may still be located on the market in extremely rare and small amounts.
CHEMISTRY BEHIND PRIMOBOLAN / METHENOLONE
(Methenolone + Acetate Ester)
Chemical Composition: 17beta-Hydroxy-1methyl-5alpha-androst-1-en-3-one
Molecular weight of base: 302.4558
Molecular weight of Acetate ester: 60.0524
Effective dose: (Men) 50-150mgs/day; (Women) 25-75mgs/day
Active Life: 4-6hrs
Detection Time: 4-5 weeks
Anabolic/Androgenic Ratio (Range): 88:44-57
Methenolone is a derivative of dihydrotestosterone (DHT) or more specifically a structurally altered form of DHT. A double bond at carbon one and two is added to the DHT hormone, which in turn greatly increases the hormone’s anabolic nature. It in addition carries an added 1-methyl group that secures it from hepatic breakdown. The addition of the Acetate ester further protects it from hepatic metabolism.
As an oral steroid, Primobolan is one of the only oral steroids that isn't a C17- alpha-alkylated (C17-aa) steroid. Typically lacking the standard C17-aa structure, this also means oral Primobolan isn't toxic to the liver. Even now, while this is a perk, utmost will find oral Primobolan to be a fairly mild or indeed a weak steroid compared to numerous others in a performance-enhancing capacity.
SIDE EFFECTS OF PRIMOBOLAN / METHENOLONE
As much as Primobolan is touted by athletes and bodybuilders as being a ‘mild’ anabolic steroid, it still exhibits suppression of endogenous Testosterone production and HPTA function.
In fact, studies have confirmed that at even an exceptionally low dosage (30 – 45mg daily), test subjects experienced 15 – 65% suppression of natural endogenous Testosterone production. Being that those dosages are as far lower than what is ordinarily required for performance enhancement purposes, it is still heavily recommended to perform a proper PCT (Post Cycle Therapy) following the discontinuation of Primobolan.
Primobolan is a DHT-derivative, typically meaning it is a modified form of DHT (Dihydrotestosterone). So, it includes with it numerous similar properties and unique characteristics, including the evident inability to aromatize into Estrogen at any effective dose used. Hence people who are concerned about Estrogenic side effects, such as bloating, gynecomastia, elevated blood pressure as a result of water retention, etc., can be relieved.
Although the oral format of Primobolan is C-17 Alpha Alkylated (also known as Methylation), which is a process that tends to make oral compounds present a degree of possible harm to the liver, Primobolan has never shown any measurable hepatotoxic effects on the body.
Although oral Primo does not impose any measurable negative effects on the liver, it still presents some minute amount of hepatotoxicity and this should still be understood, especially when it invariably comes to extended cycle lengths and/or very high dosages.
Although it is a mild steroid, the side effects of Primobolan can include intense, adverse androgenic reactions. Androgenic side effects include acne and accelerated hair loss in those fitted to male pattern baldness and body hair growth.
Few should not have a problem with acne unless they're veritably sensitive to acne, to begin with. However, hair loss is a different story. If you aren't predisposed to male pattern baldness, there's no possible threat of hair loss. However, Primo is well-known known for accelerating the process dramatically in many men, if you're predisposed.
Although it carries a mild nature, the androgenic nature of Primobolan is capable enough to ostensibly promote virilization symptoms in women. Similar effects may include body hair growth, a deepening of the vocal cords, and clitoral enlargement.
While possible, such profound effects are strongly tied to individual perceptivity.
Nevertheless, of the cure, if virilization symptoms begin to occur you must discontinue use. However, they will fade down fleetly, if use is discontinued at the onset of mild symptoms. However, if symptoms are intentionally ignored and used, continue, may veritably well become unrecoverable.
The side effects of Primobolan can include cholesterol issues, especially HDL cholesterol repression or reduction. It can additionally lead to increases in LDL cholesterol.
Primobolan, effect on cholesterol will be stronger than testosterone. It'll also be more capable than the Nandrolone and Trenbolone hormones. Still, it should be considerably lower than utmost oral steroids.
Healthy cholesterol echelons can be maintained with this steroid, but you must provide a little effort to it. Ensure your nutritious diet is cholesterol friendly, high in omega fatty acids, and low in saturated fats and simple sugars. Cinching you apply plenitude of cardiovascular activity into your routine is equally important.
CYCLES AND USAGE OF PRIMOBOLAN / METHENOLONE
Primobolan cycles are commonly in the form of fat loss and/or cutting cycles. It is practically never used as a bulking or mass-gaining agent, and most of its use is in the form of a pre-contest drug in the final weeks leading up to a competition show or photo shoot.
In a therapeutic setting, standard male Primobolan doses will fall in the 100-150mg per day range. Performance level doses will on top fall in a similar range. However, many men have reported decent results with as little as 50-75mg per day.
More excessive doses can be tolerated fairly well, but most will keep it in the listed ranges. Most men will assuredly find this dosing range is perfect when it is typically coupled with other anabolic steroids. Common stacks may properly include Trenbolone, Masteron, Anavar, or Winstrol.
Regardless of the dose, an 8-week run of Primo is standard. This does not mean the continuous cycle remains necessarily 8 weeks long but this is the standard Primo portion of the cycle.
Although it has been successful in female treatment plans, Schering has not released a standard dosing guide for females. In performance circles, the standard female Primobolan dosing range will be 25-50mg per day. Most women should be capable to tolerate such a dose fairly well.
However, most women will find a better plan will be a more moderate dose of Primo along with a steroid like Anavar. If Anavar or another anabolic steroid is added, you will want to keep the Primo dose low or it will enhance virilization probability. Regardless of stacking, a first Primobolan cycle should start with 25mg per day and no higher. Total use should not extend beyond 6 weeks. Most will find 4-6 week increments to be perfect.
Primobolan dosage and administration depend completely upon which form is being used: oral or injectable. Medical prescription Primobolan dosages outline 200mg as a first dosage, followed by 100mg every week for the complete duration of therapy.
The medical condition being treated would determine what the actual full Primobolan dosage is. The range can be anyplace from 100mg every one or two weeks to 200mg every two to three weeks. Medical guidelines for oral Primobolan dosages call for 100 – 150mg per day for no longer than 6 – 8 weeks of consistent use.
Oral Primobolan dosages begin in the range of 50 – 100mg per day for beginners, 100 – 150mg per day for intermediates, and 150 – 200mg for advanced users. Female oral Primobolan dosages are typically recommended to be within the range of 50 – 70mg per day and should present little risk of virilization. If virilization is seen in women, it is recommended to stop the usage of the drug so that symptoms would subside.
Oral Primo should be administered once per day with no requirement to split up dosages throughout the day, as its half-life is about 2 – 3 days. Injectable Primobolan exhibits a half-life of 7 – 10 days due to the Enanthate ester and should be administered twice per week, with each injection spaced evenly apart, to maintain stability and steady blood plasma levels.
HOW TO BUY PRIMOBOLAN / METHENOLONE
Pharmaceutical grade Primobolan is long tended, as most pharmaceutical grade Primo was pulled from the market long ago, even internationally. Therefore, those looking about for how to buy Primobolan, will broadly only have luck with the underground lab (UGL) manufactured products. With that being said, a precise, small amount of human-grade pharmaceutical Primobolan exists on the market, and the oral format is rarer than the injectable.
There are several alternative ways how to buy Primobolan. The most common and most popular these days tend to be internet sources (either e-mail order sources, or websites). Secondary to that is in-person ‘gym’ sources that deal with those looking to buy Primobolan in-person and generally go through cash transactions. Prices can vary depending on the source type.
However, prices generally land in the following ranges. On the expensive end, Injectable Primobolan can range from $200 – $230 per 10ml vial that is dosed at 100mg/ml for a UGL product, while pharmaceutical product is as high as $20 – $25 for a single 1ml glass ampule dosed at 100mg/ml. On the lower end, one can find UGL grade injectable Primobolan for $90 – $130 per 10ml vial dosed at 100mg/ml and pharmaceutical products can be $12 – $18 for a single 1ml glass ampoule dosed at 100mg/ml.
Oral Primobolan on the expensive end can range from $2.50 – $3.50 per tablet (50mg tablets) of UGL origin and pharmaceutical grade is even more expensive at $105 – $120 for a lot/bottle of 50 tablets at 25mg per tablet. On the lower end, oral Primobolan can be found for $1.50 – $2.50 per tablet containing 10mg per tablet of UGL origin.
If you buy Primobolan online and you live in the United States you are breaking the law. In the U.S. anabolic steroids are classified as Schedule III controlled substances by way of the Steroid Control Act of 1990. An act that was later reinforced by the Steroid Control Act of 2004.
Those who violate this law may incur harsh penalties that may include hefty fines and prison. The laws revolving around anabolic steroids can vary greatly from one country to the next, but the U.S. is about as strict as it gets. Some countries are similar to the U.S. regarding steroid law, but others are far more lenient. Before you buy Primobolan or any anabolic steroid, it is imperative you thoroughly acknowledge the law as it pertains to where you live.