Nolvadex-Tamoxifen For PCT 2023, Complete Guide.

Nolvadex/Tamoxifen Complete Guide, Dosage, Benefits, Side-effects, Treatments, and Other Related Details.

In this article, a comprehensive analysis of Tamoxifen-Nolvadex, the drug that serves as the finest post-cycle treatment option, is provided. This article will go into some of the particulars on why Nolvadex has been advised for bodybuilders, as well as some adverse effects that most people fail to understand before beginning the use of this medicine.

What are SERMs - Selective Estrogen Receptor Modulators?


SERM – Selective Estrogen Receptor Modulators are a category of medicine that can help in preventing certain kinds of breast cancer. However, this compound is also used by healthcare professionals to treat Osteoporosis. Osteoporosis is a bone disease that appears when bone mass and bone mineral density decrease or when the quality or structure of bone starts to decline. SERMs such as Nolvadex, Evista (raloxifene), and Soltamox are medications that can be used for the suitable treatment of Osteoporosis and Breast Cancer.

SERM – Selective Estrogen Receptor Modulators are also used as hormone therapies that control how estrogen functions in the human body. Apart from this, bodybuilders can use SERMs for their distinct needs. Below are the following drugs that are commonly prescribed to bodybuilders to be consumed during Post Cycle Therapy – PCT:

Selective estrogen receptor modulators - SERMs such as Clomid and Nolvadex, which should not be confused with SARMs, control post-cycle estrogen production and counteract its harmful effects on the body. When an athlete or a bodybuilder proceeds towards the end of the anabolic steroid cycle, their bodies can experience a rush of estrogen, which results in hormonal disbalance. At this point, Post Cycle Therapy supplements such as Clomid and Nolvadex are essential to be used. It helps in the reduction of harm by restoring natural hormonal balance. Nolvadex is an effective drug for managing estrogen levels and preventing estrogen spikes that can cause major health concerns like heart disease, prostate disease, and stroke. In this article, we will talk about Nolvadex and how it can be efficiently used to fix health problems caused by the use of the steroid cycle.

Introduction to Nolvadex PCT

Nolvadex Tablet Form

Oftentimes, when coming off a steroid cycle, bodybuilders might notice a slight decline in their gains and overall endurance. To maintain these gains and stabilize natural hormonal production, the body requires Post Cycle Therapy supplements. The PCT will support counteracting all the side effects of the drugs and fighting rising estrogen levels. Without a proper PCT supplement, not only will you suffer from liver toxicity, but you will lose all your gains and only have low testosterone levels in the body to show for it. It is observed that professional bodybuilders and athletes use both Clomid and Nolvadex in PCT, frequently mixing these two medications with HCG to jump-start the body's natural testosterone production.

In this article, we focus only on Nolvadex and its effects on the human body. Nolvadex is a brand name, and the active ingredient in it is known as Tamoxifen, which is present in other brand names as well. It is just that Nolvadex is the most popular compound and is used as a generic term in bodybuilding regimens. It has a shelf life of 36 months in tablet form. The choice between Clomid and Nolvadex depends only on your particular individual circumstances and body type. The argument over whether Clomid or Nolvadex is preferable has been raging for years between bodybuilders. Nolvadex is considered milder than Clomid and has been shown in research to produce better testosterone level progress over several weeks when compared to Clomid. It is the most extensively sold PCT supplement because of these traits. Clomid is more powerful than Nolvadex in the short term. Both supplements stimulate the production of GnRH, which in turn causes the pituitary gland to produce more luteinizing hormones, which raises the levels of testosterone.

Working Mechanism of Tamoxifen (Nolvadex)

Nolvadex Supplement

Tamoxifen works by hindering the negative effects caused by steroids in the human body. This compound acts as an estrogen antagonist in the brain and the breast area, which means it prevents estrogen from exerting its normal effect in those areas. As an agonist, Nolvadex carries out a duty like that of estrogen within the human body.

Nolvadex and Tamoxifen Citrate are both the same compounds. Tamoxifen does not directly decrease estrogen activity in the body. It binds to estrogen receptors, inhibiting attachment and ceasing its function. People who use steroids seek this function as it inhibits estrogen activity while taking anabolic steroids. This stops the conversion of testosterone to estrogen, which, during a cycle, can mean that estrogen levels remain low. Although bodybuilders frequently view low estrogen as advantageous, it’s not.

Uses of Tamoxifen - Nolvadex

Tamoxifen - Nolvadex is well regarded throughout the medical community as well as among fitness enthusiasts and professional steroid users. Tamoxifen is valued in both categories, that is, medically and for steroid users. Its key objective is to block selective estrogen receptors in the breast tissues. The condition known as gynecomastia (man boobs) that arises among bodybuilders after the use of steroids is treated by Nolvadex. This condition occurs in almost every steroid user because of unbalanced levels of testosterone and estrogen. Nolvadex is an effective drug in the treatment of gynecomastia, post-cycle syndrome as well as other estrogen-related conditions. Tamoxifen is used during both the PCT cycle and in the treatment of breast cancer. It accomplishes this by successfully hindering a rise in estrogen levels, which, if it happened, would cause the cancer to spread to the breast region.

This compound is widely used as a PCT Supplement to avoid the side effects that occur from the use of anabolic steroids. Tamoxifen aids in restoring natural hormone levels in the body after the execution of a steroid cycle. Most importantly, this compound handles testosterone suppression and gynecomastia, which is a great concern for bodybuilders and athletes. Hence, it sums up that Nolvadex (tamoxifen) provides numerous lifesaving advantages to the bodybuilding world.

Dosage of Nolvadex for Anabolic Steroid Users

Supplement Facts

The most effective use of SERMs is when consumed with the guidance of a professional healthcare provider.

Steroid users often be burdened by gynecomastia. To prevent this problem, tamoxifen (Nolvadex) is prescribed by their trainer or medical practitioner. It can be used during the steroid cycle. Tamoxifen (Nolvadex) is a cost-effective, easy, and risk-free solution to prevent gyno.

According to the advisable dosage pattern for normal testosterone drop, tamoxifen is taken at the beginning of the PCT cycle. It should be initiated with a low dose of 10mg. Later, if a user is doing fine with this dose, then the dosage can be increased to 20mg next week. It shows results after binding to breast tissue receptors and inhibiting the effects of estrogen.

If Tamoxifen (Nolvadex) is not effective at this dose pattern due to the steroid's strong aromatization, increase the dose. The dose of this SERM depends on the specific conditions. The detailed dosage is mentioned in the link; click here to find out.

Take Nolvadex exactly as prescribed by your doctor, either in a single dose with meals and a large glass of water or split into two doses (given in the morning and the evening). Do not chew or crush the pills.

Dosage of Nolvadex PCT for Women

Women can regard Nolvadex tamoxifen as a safer performance enhancement compound due to its ability to lift testosterone levels, which is the same reason why steroids are used. This SERM has a tendency to enhance women's body composition and boost endurance without the danger of steroid after-effects, resulting in a tighter and leaner physique.

It is advisable by professionals that Nolvadex 10mg daily is an effective dose for females. Results will be visible in a few weeks.

Dosage and Cycle of Nolvadex Tablet for Men

Nolvadex is used in higher doses of PCT to prevent the development of male breast tissue, called gynecomastia, as discussed above. A higher dose helps to stimulate the natural testosterone release.

It is advisable to do four to eight weeks of Nolvadex PCT, according to your preference. Occasionally, it can be used in combination with other compounds, such as Aromatase Inhibitors and HCG, for effective results.

Men are expected to take 40mg of Nolvadex tablets during the first half of the cycle. The dose can be reduced to 20 mg per day during the latter half of Tamoxifen PCT.

Men who face strong testosterone suppression can start the cycle at 100 mg per day or 75 mg, as per their wish. Below is the advisable pattern for the Nolvadex PCT cycle for men:

  • Week 1 – 75mg/day
  • Week 2 to 3 – 50mg/day
  • Week 3 onwards – 25mg/day

The cycle’s duration depends on the steroid’s active life a bodybuilder used earlier. If the steroid is a short ester, a steroid user must begin PCT around the time when their steroid cycle is coming to an end. On the other hand, they must wait up to two weeks before beginning PCT with Tamoxifen/Nolvadex and other substances if the steroid is a long-acting one.

Different Forms of Nolvadex PCT Available in the Market

Below is an image of the Capsule form of Nolvadex


Below is an image of the Liquid Form of Nolvadex.


Tamoxifen in pill form, also called tamoxifen citrate (brand name Nolvadex), and in liquid form (brand name: Soltamox). 

Other Treatments Performed by Nolvadex – Tamoxifen

  • Breast Cancer
  • Breast Cancer in Males
  • Neoplasia - Estrogen Dependent
  • Breast Cancer - Adjuvant
  • McCune-Albright Syndrome
  • Precocious Puberty

Advantages of Nolvadex PCT

Muscle Formation

When it comes to the wave of testosterone bounce-backs, Nolvadex PCT and Clomid PCT are the only two supplements that are consistently mentioned and advised for anabolic steroid users.  Nolvadex is well-known for its mild side effects. It's milder than Clomid, yet its performance for bouncing testosterone levels back to normal is much better. Nolvadex tablet is easily available in the market at economical rates. Few previous research on healthy men has demonstrated that Nolvadex and clomid both these SERMs have a tendency to increase testosterone by 100% in just a few weeks. It was also found out after the studies that the ingredient present in Nolvadex, which is Tamoxifen, can help with coronary artery disease in long-term treatment. It can reduce cholesterol levels by downregulating cholesterol synthesis, thanks to its ability to prevent delta 8-cholesterol from being converted to lathosterol.

The most important perk of Nolvadex for bodybuilders is that it suppresses estrogenic action in breast tissue to prevent gynecomastia, for which it can work rather well during a cycle. Other than the benefits of gyno, there are several other perks provided by the Nolvadex PCT cycle listed below:

  • It is easy to consume in capsule/tablet form.
  • Nolvadex in bodybuilding can restore imbalanced hormones.
  • It also releases stress.
  • Nolvadex PCT can lower the other side effects of steroids.
  • It prevents acne on the face and body.
  • It regulates blood pressure and cholesterol levels in the body.
  • It hinders oily skin.
  • There will be no hair loss during the Nolvadex pct cycle.
  • It minimizes the risk of breast cancer and cancer recurrence.
  • Tamoxifen can be used to treat osteoporosis, which is bone mineral loss.
  • Tamoxifen can assist in achieving health and fitness during steroid use.

Side Effects of Nolvadex PCT

Steroid users often ignore the potential side effects of Tamoxifen / Nolvadex because of the drug’s specific targeting of a few body areas. It is crucial to keep in mind that every compound has few side effects, and each body reacts to compounds in its unique way.

Nolvadex can suppress the production of the peptide hormone IGF-1 in the liver. IGF-1 in the body is an essential compound for the growth of muscle tissues. The capacity of tamoxifen to reduce IGF-1 levels is another factor that makes tamoxifen use unsatisfactory for the purpose of gaining muscle mass. High IGF-1 levels play a significant role in the process of developing a better physique. Tamoxifen can enhance levels of sex hormone binding globulin (SHGB), which acts to bind to testosterone, thus reducing free testosterone in the body. A recent study has demonstrated that a rise in total testosterone by the use of Nolvadex PCT occurs, but it also lowers free testosterone in the body. Tamoxifen, when lowering free testosterone, can affect bodybuilding gains.

Common Side Effects of Nolvadex PCT Include:

Tamoxifen's focused effects on specific body areas led some steroid users to ignore the drug's negative effects. A number of adverse effects are possible when SERM medicines are used clinically. The following is a list of some of the most typical adverse effects.

  • Hot flashes
  • Disturbed menstrual periods,
  • Nausea
  • Leg cramps
  • Abdominal cramps
  • Bone pain
  • Muscle pain
  • Cough
  • Fatigue
  • Hair thinning
  • Headache
  • Depression
  • Loss of sexual ability

Inform your doctor immediately if you have any unlikely but severe Nolvadex side effects, such as:

  • Vision changes (e.g., blurred vision),
  • Eye pain
  • Easy bruising or bleeding
  • Mental/mood changes
  • Swelling of ankles or feet
  • Unusual tiredness

Serious Risks of Taking Tamoxifen

Rarely, tamoxifen may cause serious problems in the human body, such as:

  • Blood clots, deep vein thrombosis (DVT) and strokes.
  • Cataracts or other eye problems.
  • Endometrial (uterine) cancer.
  • Fatty liver in women leads to liver cancer.


Tamoxifen (Nolvadex) is undoubtedly the prime product for post-cycle therapy and can be used during or after the steroid cycle. You can also use it alongside Clomid.

If you are looking to enhance your performance while training with SARMs or steroids, or you may have questions relating to Post Cycle Therapy – PCT, then visit the SteroidWiki page to make an informed decision. In order to help you plan your fitness routine, we have put together a thorough, comprehensive guide in our article section. Explore and have fun!


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