Melanotan I Complete Profile, Dosage, Usage, Pros & Cons
Table of Contents
Introduction
Naturally tanned and golden glowing skin is a desire of many people because of the mesmerizing look that comes with it. People who adore tanned skin always try sunbathing. However, spending long periods under the sun can come up with sunburn, dehydration and rashes. If you are looking to avoid all these effects caused by direct sun rays then you may use Melanotan I.
Thanks to the advancement in the research field developed peptides called Melanotan I and Melanotan II. Both of these peptides mimic the functionality of an endogenously occurring hormone, which results in desired skin colour. With the right amount of dosage, melanotan I can assist you to attain perfect tan skin without exposing yourself to direct sun rays for a long time.
Key-Points
What is Melanotan I?
Melanotan I also called Afamelanotide, with 13 amino acids chain length is a synthetic peptide that has a linear formation. It is a specific drug aimed to treat light-related skin conditions. This peptide also prevents people from skin cancer. Moreover, Melanotan I can also be used for body tanning and can be taken through injections or nasal sprays. Melanotan molecules come in two different varieties: Melanotan I and Melanotan II. Both of them have been connected to enhanced skin tanning and melanin synthesis. Alpha-melanocyte stimulating hormone (a-MSH), which is produced by the hypothalamus and is known to have a high affinity for the various melanocortin receptors found throughout the body, is the primary hormone that both peptides imitate in their mode of action.
The period of tanning effect attained from this peptide depends upon various factors if consumers cease administering it. The majority of users, however, will observe that the tan produced by the medicine will progressively disappear four to eight weeks following the last dose.
Melanotan I Mechanism of Action
Melanotan I is injected after which it starts to mimic the functionality of a natural hormone in the body called alpha-melanocyte-stimulating. This hormone then binds to melanocortin receptors and stimulates the pigment melanin in skin cells. As a result of this, skin appears darker as more production of melanin in skin cells causes more darkened skin.
Few studies have represented that Melanotan I is more powerful and effective than Melanotan 2 before being broken down by enzymes. Melanotan 2 combines with a vast range of receptors than Melanotan I and it also has a shorter life in the human body. This procedure has positive effects on a variety of skin-related disorders as well as reducing sun damage to skin exposed to ultraviolet wavelengths.
Usage of Melanotan I
1. Treats various Skin Disorders
Experiments and evidence reveal that the capability of Melanotan I to enhance the production of skin pigment melanin is lucrative in the treatment of several skin conditions such as:
- Erythropoietic Protoporphyria, is an uncomfortable skin condition brought on by sensitivity to sunlight.
- Vitiligo; pale white skin patches
- Mild to moderate acne
- Polymorphic Skin Sensitivity; skin rashes caused by sun exposure
- Pre-cancerous skin lesions of hands, head and forearms in patients who had an organ transplant
2. Prevents Heart Disease
It has been discovered that Melanotan I controls crucial cardiac protection mechanisms.
- It helps to relax heart arteries which aid in better blood circulation around the body.
- Melanotan I also assist against cardiovascular disease by raising the level of nitric oxide, a chemical compound that relaxes heart arteries to enhance blood circulation.
- This peptide also maintains heart dysfunction and prevents the formation of plaques.
3. Fights Inflammation
Research has reflected that Melanotan I has anti-inflammatory properties that can help ward off a broad range of diseases.
- Convince antioxidant activities, stimulates DNA repair, and modulate the inflammatory process.
- Helps in nerve pain injury.
- Melanotan I reverse intestinal inflammation hence bowel inflammation is managed.
4. Lowers Blood Pressure
In previous studies performed on hypertensive mice, Melanotan I protected against high blood pressure in mice while having no negative effects on animals with normal blood pressure.
5. Improves Cognitive Function
Through research, it was deduced that Melanotan I can protect one against cognitive dysfunction related to brain disorders. It boosts neurogenesis which is nerve cell formation. This peptide also causes long-lasting neuroprotective effects.
6. Promotes Recovery following a Stroke
Administration of Melanotan I and Melanotan 2 after a stroke lowers brain damage. It then improves the recovery of memory and learning.
7. Promotes Fat Loss
Melanotan I has been shown to have the ability to burn fat by activating the MC5R.
8. Improved mood and outlook
Melanotan I when used in conjunction with photodynamic therapy (PDT), which uses light and photosensitization to kill cancer cells, delivers psychological benefits to patients, such as improved mood and perspective.
Dosage of Melanotan I
Dosage Frequency: Once daily
Dosage Amount: 250mcg (0.25mg) – 2000mcg (2mg)
Melanotan I is available in the form of powder which should be reconstituted with bacteriostatic water or sterile water.
Inject 0.15 ml once every day for one to two weeks, followed by 0.25 ml twice per week for maintenance. The correct mode of administering this peptide is a subcutaneous injection to the abdominal area. Melanotan I is also available in the form of nasal sprays.
It can take weeks to months of administering Melanotan I to observe the effective outcome of your desired skin complexion. Without first seeking the advice of a medical practitioner, it is not advised that persons who are pregnant or nursing take this medication. Melanotan I should be stored in the refrigerator yet it is secure outside of the refrigerator for approximately 7 days.
Chemical Structure of Melanotan I
Health Perks Attained from Melanotan I
Along with the rewards of offering a tan without the need for extensive exposure to sunlight as well as improved sexual performance, Melanotan I also may assist to minimize the appetite by targeting an appetite-suppression receptor in the brain.
Although this effect is not particularly strong, most users are aware of it and find it appealing. Other common health benefits of using Melanotan I are mentioned in the list below.
- Treats several skin conditions
- Avoid heart disease
- Maintains blood pressure
- Combat inflammation
- Enhances cognitive function
- Promotes recovery after stroke
- Facilitates fat loss
- Manage appetite
- Acne treatment
- Improved mood
- Increased sexual desire and performance
Associated Side Effects of Melanotan I
The side effects of this peptide are very rare. Melanotan I is a safer and more favourable profile according to research. There have been no reported safety concerns, drug-related adverse effects, no deaths or any other adverse events.
Side effects associated with Melanotan I may include face flushing, increased number of moles and freckles, gastrointestinal upset, loss of appetite, feeling of tiredness, nausea, stomach upset, vomiting and unwanted tanning.
There are no more harmful side effects associated with the use of Melanotan I if consumed in the right amount. If you feel like your symptoms are worsening, then do visit your doctor immediately.
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