Cardarine GW-501516 Complete Profile, Dosage, Results, and Other Relevant Information

What is Cardarine GW-501516?

Vial containing Cardarine GW-501516

Cardarine, commonly known as GW501516, is a synthetic substance that regulates metabolism. A potent substance called Cardarine GW-501516, a Selective Androgen Receptor Modulator (SARM) that fights the AR, was first created to address the loss of muscle mass brought on by major disorders (such as muscular atrophy, Cancer, HIV/AIDS, or aging).
Originally, this substance was not created for usage in the fitness sector. Instead, it was primarily used to treat muscle mass loss, a common side effect of several chronic illnesses, including AIDS, AIDS-related muscular atrophy, and even some forms of Cancer.
But over time, this characteristic made the substance rather well-liked by athletes, who began using it for their benefit. 
Cardarine is not a naturally occurring SARM but is synthesized in laboratories to achieve the same results. These supplements promise to help increase bone density and enhance overall body strength.

Structure

Structure of Cardarine GW-501516

 

History of Cardarine

Cardarine (also known as GW-501516) was initially developed in the early 1990s by Glaxo Smith Kline and Ligand to inhibit the growth of tumors in the colon, prostate, and breast. During the early clinical trials of GW501516, however, researchers noticed that it also altered the body's cholesterol levels. As a result, when it was originally introduced, it was touted as a technique to lower bad cholesterol or LDL.
However, the fitness and sports industries quickly discovered a new application for Cardarine. Gw501516 may boost acid metabolism and endurance. Athletes and bodybuilders might recover quicker after training, pulling bigger weights, and exercising longer. It might even burn off excess body fat, which is great news for gymgoers looking to get those six-pack abs!

Cardarine was being utilized by bodybuilders and professional athletes worldwide by the mid-1990s. Then, in 2007, research revealed that mice given GW501516 had improved physical performance. Cardarine was soon used as a doping substance by sportsmen, including numerous members of the 2008 Olympic teams. The World Anti-Doping Agency (WADA) and numerous sports commissions responded by banning the supplement.

However, if you aim to bulk up and burn fat rather than win a gold medal, Cardarine should be one of the supplements you consider. Its features make it one of the greatest on the market for many bodybuilders.
 

Uses

Uses of Cardarine GW-501516

Your body naturally manufactures components that are important in the production of Cardarine. When you need it in large quantities, an external supply is required, and Cardarine comes into play.
According to numerous studies, it may aid in improving the body's general metabolism, stabilizing blood cholesterol levels, and improving blood pressure. 
GW-501516 is a synthetically produced Cardarine with certain negative effects on your body. When a person utilizes SARMs regularly, it puts the body under stress, causing more harm than good. When someone consumes this synthetic chemical daily, it raises the body's natural concentration of Cardarine. 
Athletes and bodybuilders frequently inject it into their bodies for the greatest results, which can lead to drug dependence after a while. When the body becomes accustomed to a certain level of increased Cardarine, it does not respond as it should. The user must move to a larger dose during this period, which gradually increases.

Side effects of Cardarine GW-501516

Below are a few side effects that Cardarine causes. 

●    High chances of developing Cancer


According to the few clinical trials completed worldwide, synthetically created Cardarine, such as GW-501516, frequently increases the odds of developing Cancer. A study found that when the levels of Cardarine in your body rise, frequently owing to an external source, it causes Cancer due to its carcinogenic qualities. The consequences are similar to smoking, which is one of the leading causes of lung cancer. Even if the type of Cancer caused by GW-501516 has yet to be determined, knowing that one has a greater risk of developing the disease after eating GW-501516 is already highly concerning.

●    Damages the Brain

Cardarine impacts nearly every cell in your body. It has been demonstrated that utilizing synthetically created substances over time can cause brain cell damage. Neurons make up the brain. It is the only cell in the body that does not renew after the birth of a kid. When brain cells, or neurons, are injured, it is a permanent loss, and nothing can be done to reverse the process. An elevated concentration of Cardarine in the bloodstream has also been linked to brain inflammation because it functions as a stimulant for the cytokine Interleukin 6.

●    Severe Headache

It is one of the most frequently reported negative effects of GW-501516 use. People who have used this product for a long time have even mentioned this issue. Overdoes or abusers of this chemical are more likely to get headaches. Cardarine is a stimulant for the body; thus, taking too much of it creates severe headaches. 

●    Messes with the cardiovascular system

GW-501516 has been shown in numerous studies to considerably raise the heart rate. When consumed in excess, it puts a lot of strain on your heart, causing it to beat quicker and raising your total heart rate. 

It affects the individual's blood pressure since it increases the heart rate. People who took GW-501516 regularly displayed a typical pattern of persistently elevated blood pressure. Under normal conditions, a person with high blood pressure is frequently given medications to assist in regulating the pressure. However, when someone is taking synthetically made Cardarine, these medications are ineffective since the substance is far more powerful than the prescriptions. In that case, the only way to bring the blood pressure back to normal is to get off GW-501516 and follow a professional doctor's prescription.

●    Muscle Cramps and Joint Pains

It is fairly typical to experience joint discomfort after taking GW-501516. In most situations, the pain becomes so intolerable that the customer must begin physiotherapy or other therapies to alleviate the discomfort. Muscle cramps are another typical adverse effect seen by most GW-501516 users. Regular drugs are required to treat severe cramps, making it difficult to live a healthy lifestyle. 

●    Damages the Liver

Creatinine has a negative effect on the body. When consumed in excess, it has a direct influence on their kidneys. Similarly, GW-501516 has a negative impact on your liver. Constantly high levels of Cardarine have been linked to liver damage. It is a medical disorder in which your liver begins to expand due to excessive Cardarine exposure. 

As a result of liver toxicity, various complications arise, many of which are connected to the disease. The individual first experiences skin yellowing, followed by nausea, vomiting, weight loss, itching, stomach discomfort, and other symptoms. When these factors combine, they cause lasting liver damage, increasing the likelihood of developing additional liver illnesses. 

●    Stomach Upset

When a person starts with Creatinine, diarrhea is quite common. When taking antibiotics with GW-501516, most people have diarrhea. It is because the medicine disrupts the mechanism of GW-501516, resulting in severe gastrointestinal troubles. Regular ingestion of pharmaceutical medications, GW-501516, is a significant difficulty for all those suffering from chronic ailments. 

Dosage of Cardarine

Cardarine at 10mg/day is an excellent starting dose. Of course, the larger the dosage, the better and faster the outcomes, but you also expose yourself to additional health hazards if you take dosages over these quantities. 
The following is a dose chart for Cardarine: 

  • 10mg/day for beginner's dosage
  • 15mg/day for mediums dosage
  •  20mg/day for advanced dosage.  

Benefits of Using Cardarine GW-501516

Benefits of Using Cardarine GW-501516

The various advantages of using Cardarine include:

●    Controls atherosclerosis

GW501516 inhibits atherosclerosis, or the buildup of plaque in the arteries, which is a major cause of heart disease, heart attacks, and stroke.  In several clinical studies, rats who took GW 501516 had higher levels of good (HDL) cholesterol and lower levels of bad cholesterol. Remember that Cardarine was originally advertised as an anti-cholesterol medication; thus, this benefit is well-shown.

●    Increase in endurance

This is one of the most important reasons for utilizing GW-501516. Furthermore, endurance rises several times, resulting in significantly improved athletic performance. As a result, users of this substance may exercise considerably harder and for longer periods than others, resulting in superior outcomes. 

●    Prevent Type 2 Diabetes and obesity

GW501516 can potentially help prevent or treat Type 2 Diabetes and obesity.

●     Increased Fat Burning

Cardarine enhances the mitochondrial count in the body. This organelle is important in the creation of energy in our bodies. When the body's energy level rises, so does its metabolism. This results in far better and faster fat burning, resulting in a more energized sensation while growing lean muscles. 

●    Improve the performance of Athletes

Cardarine is often used to boost performance. Athletes can perform better due to enhanced metabolism. They have greater energy and can work out for longer periods of time, resulting in better outcomes. 

The bottom line

Cardarine, or GW501516, is a synthetic compound originally researched for treating various health problems. It later acquired popularity due to its possible performance-enhancing properties.

Cardarine, while sometimes mislabeled as a SARM (selective androgen receptor modulator), belongs to a family of medications known as PPAR agonists, which can change energy metabolism in the body.

The main alleged advantages are weight loss, diabetes and obesity benefits, better blood lipids, and increased sports performance, while human research in these areas is limited. The drug's propensity to trigger fast cancer development in rats and mice was the most significant adverse effect revealed during the initial study. It is uncertain whether this also applies to people.

Read more about SARMS on steroidwiki articles. 

References

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  4. GW501516 (2023) Wikipedia. Wikimedia Foundation. Available at: https://en.wikipedia.org/wiki/GW501516 (Accessed: 9 November 2023).
  5. Mawer, R. (2020) How Creatine Boosts Exercise Performance, Healthline. Healthline Media. Available at: https://www.healthline.com/nutrition/creatine-exercise-performance#bottom-line (Accessed: 9 November 2023).
  6. Advertorial, T. (2023) Partner Content: Cardarine GW-501516 Review - Uses, Side Effects, Dosage & Benefits, NDTV.com. Available at: https://www.ndtv.com/partner-content/health-supplements/cardarine-gw-501516-review-uses-side-effects-dosage-benefits-3947637 (Accessed: 9 November 2023).
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